RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Mapk3
RNA ID
RNA Type
mRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
qRT-PCR; Western Blot etc.
Target
NA
Pathway
NA
PubMed ID
Title
Effects of?Nervilia fordii?Extract on Pulmonary Fibrosis Through TGF-beta/Smad Signaling Pathway
Year
2021
Function
"Similarly, the protein level of ERK1/2 was significantly downregulated, while that of p-ERK1/2 was significantly upregulated in BLM-induced pulmonary fibrosis rats. NFE (400 and 200 mg/kg) treatment significantly and dose-dependently normalized the phosphorylation of ERK1/2, upregulated ERK1/2 protein levels, and downregulated p-ERK1/2 protein levels."